Curvature Entropy Trapping of Long DNA under Hydrodynamic Flows in Microfluidic Devices
Masanori Ueda, Tetsuya Hayama, Yuzuru Takamura, Yasuhiro Horiike, Tomonari Dotera and Yoshinobu Baba
Jpn. J. Appl. Phys. 43 (2004), pp.1649-1650
We investigated the curvature effect on the dynamics of long DNA using microfluidic devices. Long DNA has larger configurational entropy in a curved channel than in a straight channel. Under weak hydrodynamic flows, long DNA exhibited a curvature entropy trapping effect. The effect disappeared as the hydrodynamic flow was increased.